Biographical Sketch:
Estevana Isaac-Nyamwaro, MD, MSCR is an Assistant Professor of Neurology and Clinical Director of Cognitive Disorders at the University of Pittsburgh. She is a board-certified and fellowship-trained cognitive/behavioral neurologist and clinical researcher. Her clinical research focuses on comparative effectiveness analysis of different interventions and strategies implemented in “real world” settings as well as clinical trials addressing pharmacological management of neurocognitive and neuropsychiatric symptoms due to neurodegenerative disease, including Alzheimer’s Disease, Lewy Body Dementia and Frontotemporal Dementia as well as non-neurodegenerative etiologies such as vascular disease. She uses principles from community engagement research, including mutual respect and equitable collaboration to help build trust and increase participation in the local communities she serves.
Training:
- Postdoctoral Research Training for the Care of Vulnerable Older Adults with Alzheimer’s Disease and Related Dementias and Other Chronic Conditions, Mount Sinai, New York, NY
- Cognitive and Behavioral Neurology Fellowship, University of Pennsylvania, Philadelphia, PA
- Neurology Residency, Thomas Jefferson University Hospital, Philadelphia, PA
Education:
- Master’s in Science in Clinical Research, Medical University of South Carolina, Charleston, SC
- Medical Degree, Meharry Medical College, Nashville, TN
Specialized Areas of Clinical, Research and/or Education Interests
Clinical: Management of cognitive and behavioral impairment due to neurodegenerative and non-neurodegenerative etiologies, which includes amyloid targeting therapy for eligible patients
Research: Comparative effectiveness research, clinical trials and community engagement
Education: Supervision and Training in the latest updates for cognitive neurology research and clinical management
Board Certifications
- American Board of Psychiatry and Neurology
- United Council for Neurological Subspecialties
Professional Organization Membership
- Alzheimer’s Association
- American Academy of Neurology
- National Medical Association
Honors & Awards
- American Academy of Neurology TRANSCENDS Scholar Award, 2023
- Claude D. Pepper Older Americans Independence Center, REC Award, 2023
- Alzheimer’s Association for Health Disparities, Policy and Ethics in Alzheimer’s Disease and Related Dementia Award, 2024
Selected Recent Publications
Isaac E, Zhu CW, Rivera Mindt M, Siu AL, Federman A, Yaffe K, Vickrey BG, Voeks J, Agarwal P, Brooks D, Ayo O, Sano M. Psychosis in Neurocognitive Disorder Among Ethnoculturally Diverse Older Persons. Neurol Clin Pract. 2025 Aug;15(4):e200509. doi: 10.1212/CPJ.0000000000200509. Epub 2025 Jul 7.
Isaac E, Saherwal AA, Alam S. Systemic thrombolysis for acute central retinal artery occlusion in sickle cell disease: Case report. J Natl Med Assoc. 2022 Dec;114(6):589-592. PubMed PMID: 36163059.
Isaac E, Ney D, Serruya M, Keith S, Lippa C, Sperling MR. Tolerability of memantine monotherapy versus adding memantine as combination therapy. J Natl Med Assoc. 2022 Jun;114(3):308-313. PubMed PMID: 35272847.
Complete List of Published Work in MyBibliography:
https://www.ncbi.nlm.nih.gov/myncbi/estevana.isaac.1/bibliography/public/
