Dr. Nacopoulos’ clinical interests focus on the diagnosis and treatment of movement disorders, including Parkinson’s disease, tremor conditions, dystonia, ataxia, Huntington’s disease, and other conditions of abnormal movement. With his specialty training, he can evaluate patients for consideration of Deep Brain Stimulation (DBS) therapy, working in close association with neurosurgery to offer this treatment to patients with Parkinson’s disease, essential tremor, and dystonia conditions. In addition, he offers patients therapeutic treatments with botulinum toxin injections, targeting conditions including focal dystonia, blepharospasm, hemifacial spasm, spasticity, sialorrhea, and chronic migraine.
Education & Training
- Fellow, Cleveland Clinic, Movement Disorders
- Resident, Cleveland Clinic, Medicine Internship / Neurology
- MD, Temple University School of Medicine, Medicine
Specialized Areas of Clinical, Research and/or Educational Interests
- Clinical: Movement Disorders
- Education: Resident Training
- American Board of Psychiatry and Neurology
Professional Organization Membership
- Member, American Academy of Neurology
- Member, Movement Disorders Society
Honors & Awards
- Neurology Residency Teacher of the Year
Selected Recent Publications
Appleby BS, Nacopoulos D, Milano N, Zhong K, Cummings JL. A review: treatment of Alzheimer's disease discovered in repurposed agents. Dement Geriatr Cogn Disord. 2013;35(1-2):1-22. doi: 10.1159/000345791. Epub 2013 Jan 9. PMID: 23307039.
Nacopoulos DA and Fernandez HH. Serotonin Syndrome. In: Friedman JH ed. Medication Induced Movement Disorders. Cambridge University Press 2015: 44-53.
Pandya M, Nacopoulos DA, and Khokhar N. Management of Treatment-Related Behavioral Disturbances in Parkinson’s Disease. Parkinson's Disease: Current and Future Therapeutics and Clinical Trials. Cambridge University Press 2016: 139-150.
Ahmed ZA, Nacopoulos DA, John S, Papesh N, Levine D, Bamford CC. An Algorithm for Opioid and Barbiturate Reduction in the Acute Management of Headache in the Emergency Department. Headache. 2017 Jan;57(1):71-79. doi: 10.1111/head.12961. Epub 2016 Nov 10. PMID: 27861834.
Phillips-Sabol J, Nacopoulos D. Lewy Body Dementia. In: Sanders KM ed. The Physician’s Field Guide to Neuropsychology: Collaboration through Case Examples. Springer. 2019: 239-254.