Education & Training
PhD, Molecular Biology, Peking University Medical School 1995-1998
Specialized Areas of Clinical, Research and/or Education Interests
Cell death mechanism, neuroinflammation and therapeutic approaches in Ischemic stroke and vascular cognitive impairment and dementia
Professional Organization Membership
- Society for Neuroscience
- American Heart Association
- International Society for Cerebral Blood Flow & Metabolism
Selected Recent Publications
- Chen F, Weng Z, Xia Q, Cao C, Leak RK, Han L, Xiao J, Graham SH, Cao G. Intracerebro-ventricular delivery of recombinant NAMPT deters inflammation and protects against cerebral ischemia. Transl Stroke Res. 10(6):719-728,2019.
- Liu Q, Bhuiyan M. I.H; Liu R, Song S, Begum G, Young CB, Foley LM, Chen F, Hitchens TK, Cao G, Chattopadhyay A, H Li, Sun D. Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function. J Neuroinflammation. 28;18(1):187,2021.
- Wang Y, Liu G, Song H, Cao C, Ji X, Cao G. Elevated lipoprotein-associated phospholipase A2 is associated with intracranial atherosclerosis. Front Neurol. 13: 858302,2022.
- Wang Y, Leak RK, Cao G. Microglia-mediated neuroinflammation and neuroplasticity after stroke. Frontiers in Cellular Neuroscience 16:980722,2022.
- Guo X, Seinman RA, Sheng Y, Cao G; Wiley C; Wang Q. An AGS-associated mutation in ADAR1 catalytic domain causes early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain. Journal of Neuroinflammation. 19:285,2022;
- Liu Z, Hermann DM, Dzyubenko E, Cao G*, Cao X*. Editorial: modulating microglia to enhance neuroplasticity for restoring brain function after stroke. Frontiers in Cellular Neuroscience. 17:1232437,2023. *Co-corresponding author.
- Weng Z, Cao C, Stepicheva N, Chen F, Cao S, Bhuiyan MIH, Wang Y, Wang Q, Foley LM. Hitchens TK, Sun D*, Cao G*. A novel needle mouse model of vascular cognitive impairment and dementia. Journal of Neuroscience. 44:7351-7360,2023. Featured article in J Neuroscience Journal, Facebook and LinkedIn.
- Mi Z, Ma J, Zeh DJ, Rose ME, Henchir JJ, Liu L, Ma X, Cao G, Dixon CE, Graham SH. Systemic treatment with ubiquitin carboxy terminal hydrolase L1 TAT protein ameliorates axonal injury and reduces functional deficits after traumatic brain injury in mice. Experimental Neurology. 373:114650,2024.
- Bhuiyan MI*, Chen F, Jahan I, Weng Z, Foley LM., Hitchens KT, Deng X, Sun D, Cao G*. SPAK inhibitor ZT-1a protects white matter integrity and improves cognitive function in mouse model of VCID. CNS Neuroscience & Therapeutics. 30(3):e14654. *Co-corresponding author.
- Lin L, Chen Y, He K, Metwally S, Jha R, Capuk O, Bhuiyan MIH, Singh G, Cao G, Yin Y, Sun D. Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation. Journal of Neuroinflammation. 2024; 21: 220.
- Stepicheva NA, Weng Z, Cao S, Cao G*. A novel mouse model for vascular cognitive impairment and dementia based on the needle-guided asymmetric bilateral common carotid artery stenosis. J Vis Exp. 2024 Nov 22;(213).
