Islam M. Zaydan, MD

Associate Professor of Neurology and Opthamology


  • Co-Director, Multiple Sclerosis and Comprehensive Care Center at the University of Pittsburgh and Multiple Sclerosis Center of Excellence at Pittsburgh VA Hospital
  • Division of Neuro-Immunology
  • Division of Neuro-Opthamology

Biographical Sketch

Dr. Zaydan’s clinical interest is to provide longitudinal care and treatment for patients with Neurological and Neuro-Ophthalmic conditions.  As a Neurologist and a Neuro-Ophthalmologist, his research is focused on studying the acute and long-term effect of inflammatory, degenerative and demyelinating diseases of the nervous system and their effect on the visual pathways and visual function. His major emphasis has been on studying Multiple and Neuro-Myelitis Optica new therapeutics and the effects of the diseases on the structure of the White matter tracts using High Definition Fiber Tractography imaging techniques.

Education & Training

  • Fellow, Medical College of Virginia, Virginia Commonwealth University, Neuro-Ophthalmology
  • Resident, Medical College of Virginia, Virginia Commonwealth University, Neurology
  • MD, Alexandria University Faculty of Medicine, Alexandria, Egypt

Specialized Areas of Clinical, Research and/or Educational Interests 

  • Research: Multiple Sclerosis and Neuromyelitis Optica
  • Clinical: Neuro- Ophthalmology (Optic Nerve diseases, oculomotor disturbances, visual function disturbances after Strokes, Demyelinating CNS diseases); Neuro-Immunology longitudinal care and treatment for patients with Neurological and Neuro-Immunological conditions
  • Education: Clinical Education of Medical Students, Residents and Fellows of Neurology and Ophthalmology

Board Certifications

  • American Board of Psychiatry and Neurology
  • American Board of Vascular Neurology

Professional Organization Membership

  • American Academy of Neurology
  • North American Neuro-Ophthalmology Society (NANOS)

Honors & Awards

  • Nominated among Best Doctors in Pittsburgh 
  • Best Clinical Teacher Awards 

Selected Recent Publications

Winser S, Smith CM, Hale LA, Claydon LS, Whitney S, Klatt B, Zaydan R and Heyman R. Balance Assessment in Multiple Sclerosis and Cerebellar Ataxia: Rationale, Protocol and Demographic Data. Phys Med Rehabil Int. 2014; 1(5): 6.  

Winser S, Smith CM, Hale LA, Claydon LS, Whitney SL, Klatt B, Mottershead J, Zaydan I, Heyman R. Psychometric Properties of a Core Set of Measures of Balance for People With Cerebellar Ataxia Secondary to Multiple Sclerosis. Arch Phys Med Rehabil. 2017 Feb;98(2):270-276. doi: 10.1016/j.apmr.2016.07.023. Epub 2016 Aug 27. PMID: 27577181.

Yeh F, Zaydan I.  Differential Tractography as a Track-Based Biomarker for Neurodegeneration”. Nature Neuroscience reference # NN-T67314