Simin Khavandagar, MD

Clinical Associate Professor

Biographical Sketch

Dr. Khavandgar’s primary interests include sleep medicine, EMG and general neurology.  She has a special interest in the interface of neurology and sleep medicine, including diagnosis and treatment of sleep disorders associated with movement disorders such as Parkinson’s disease, cerebrovascular disorders, and multiple sclerosis as well as other sleep disorders including narcolepsy, central and obstructive sleep apnea. She also has subspecialty training in clinical neurophysiology and performs diagnostic electromyography in patients with a range of neuromuscular disorders. Dr. Khavandgar participates in didactic and in clinic teaching of medical students and neurology residents as well as precepting rotating neurology residents in the sleep clinic.

Education & Training

  • MD, Tehran University of Medical Sciences, Medicine
  • Resident, University of Pittsburgh Medical Center. Neurology
  • Fellow, University of Pittsburgh Medical Center, Clinical Neurophysiology (EMG & EEG)/Sleep Medicine
  • Post Doc, Albert Einstein College of Medicine, Neuroscience

Specialized Areas of Clinical, Research and/or Educational Interests 

  • Clinical:  Management of patients with sleep disorders including sleep apnea, narcolepsy, insomnia and hypersomnia; Management of sleep disorders in patients with neurological disorders including Parkinson disease, Multiple Sclerosis, Seizure disorders and Cerebrovascular disease; Electromyography; General Neurology
  • Education:  Sleep Neurology

Board Certifications

  • Neurology, American Board of Psychiatry and Neurology
  • Clinical Neurophysiology, American Board of Psychiatry and Neurology
  • Sleep Medicine, American Board of Psychiatry and Neurology 

Professional Organization Membership

  • American Academy of Neurology
  • American Academy of Sleep Medicine

Selected Publications

Homayoun H, Khavandgar S, Hoover JM, Mohsen AW, Vockley J, Lacomis D, Clemens PR. Novel mutation in MYH7 gene associated with distal myopathy and cardiomyopathy. Neuromuscul Disord. 2011 Mar;21(3):219-22. doi: 10.1016/j.nmd.2010.12.005. Epub 2011 Jan 5. PMID: 21211974.

Khavandgar S, Walter JT, Sageser K, Khodakhah K. Kv1 channels selectively prevent dendritic hyperexcitability in rat Purkinje cells. J Physiol. 2005 Dec 1;569(Pt 2):545-57. doi: 10.1113/jphysiol.2005.098053. Epub 2005 Oct 6. PMID: 16210348; PMCID: PMC1464225.

Khavandgar S, Homayoun H, Zarrindast MR. The effect of L-NAME and L-arginine on impairment of memory formation and state-dependent learning induced by morphine in mice. Psychopharmacology (Berl). 2003 May;167(3):291-6. doi: 10.1007/s00213-002-1377-7. Epub 2003 Mar 28. PMID: 12664189.

Khavandgar S, Homayoun H, Dehpour AR. Mediation of nitric oxide in inhibitory effect of morphine against electroshock-induced convulsions in mice. Pharmacol Biochem Behav. 2003 Mar;74(4):795-801. doi: 10.1016/s0091-3057(02)01077-8. PMID: 12667893.

Khavandgar S, Homayoun H, Torkaman-Boutorabi A, Zarrindast MR. The effects of adenosine receptor agonists and antagonists on morphine state-dependent memory of passive avoidance. Neurobiol Learn Mem. 2002 Sep;78(2):390-405. doi: 10.1006/nlme.2002.4071. PMID: 12431425.